Cov nuj nqi ntawm cov poov xab β-glucan

Cov nuj nqi ntawm Poov xab β-Glucan


Poov xab yog ib qho tseem ceeb khoom noj khoom haus thiab muaj microorganism nrog ib tug loj npaum li cas ntawm beta-1,3 / 1,6-glucan nyob rau hauv nws cov cell phab ntsa. Poov xab β-glucan ntxhiab thiab ntxhiab, insoluble nyob rau hauv dej, ethanol, acetone thiab lwm yam organic solvents, nrog enhanced tsiaj tiv thaiv, anti-mob, anti-tus kab mob, anti-virus, txo cov roj uas txhaws, txhawb mob kho neeg mob thiab lwm yam kev khiav dej num, tau Ministry of Health pom zoo raws li ib tug tshiab kev pab khoom noj khoom haus, yuav muab ntxiv rau khoom noj siv mis, tej dej qab zib, ci khoom, khoom qab zib thiab lwm yam khoom noj khoom haus. Ministry of Health Ntawv Ceeb Toom No. 6 ntawm 2012 tau ncua kev siv ntawm cov poov xab β-glucan mus rau lub loj me nyuam mos liab mis mis hmoov.


Vim hais tias cov poov xab β-glucan muaj tsis tsuas zoo txhim khu kev tiv thaiv thiab lwm yam teebmeem, tab sis kuj muaj ib tug rog zoo li saj, yuav siv tau raws li cov uas tsis muaj-calorie khoom noj khoom haus additives, nyias hnav khaub ncaws, cheese analogues thiab lwm yam khov kis raws li ib tug kev hloov rau roj, nrog ntau ntau daim ntawv thov nqi.


1. Poov xab β-glucan thiab nws txoj kev ua

Poov xab β-glucan yog ib tug dej-insoluble branched polymer, lub ntsiab saw rau β-1,3 glycosides ua ke, branched rau β-1, 6 glycosides ua ke, ris rau cov poov xab ntawm tes phab ntsa qhuav nyhav ntawm 30% 35%. Los ntawm electron microscopy thiab lwm yam txhais tau tias ntawm tsom xam, zaum to taub lub spatial qauv ntawm cov poov xab β-glucan, nws molecular yuag xws li los ntawm kaum tawm txhiab mus rau ob peb puas txhiab, yog ib tug triple kauv daim ntawv.

1.1 txhim khu kev tiv thaiv

Los ntawm qhov ncauj poov β-glucan thiab lwm yam khoom noj khoom haus cov khoom xyaw yog sib txawv, lawv yuav tsis muaj mob plab thiab cov hnyuv acid los yog enzyme hydrolysis ncaj qha los ntawm cov hnyuv. Lub macrophages rau lub me me plab hnyuv hnoos qeev hlwb nqus β-glucan los ntawm cov beta-glucan receptor, thiab ces qhib rau cov hlwb tam sim ntawd. Β-1,3-D-glucan los ntawm stimulating macrophages [3], ib tug muaj peev xwm tiv thaiv thiab txhim khu lub cev ua si ib sab luag hauj lwm nyob rau hauv lub luag hauj lwm ntawm cov ntshav dawb ua si ib lub luag hauj lwm nyob rau hauv kev tiv thaiv lub cev los ntawm cov tau raug mob rau kev kho mob tsis muaj lub macrophages yog ib tug hauv chav kawm ntawv ntawm loj hlwb muab kev koom tes nyob rau hauv nonspecific tiv thaiv. Nws muaj peev xwm noj txawv teb chaws hais thiab kom lawv puas tsuaj. Macrophages kuj muab lwm tiv thaiv kab mob hlwb xws li B hlwb thiab T hlwb los muab Pib ntsais koj teeb uas tsiv rau lawv li mob qhov chaw. Nws kuj tsim txoj kev loj hlob yam tseem ceeb los kho puas cov ntaub so ntswg.

1.2 anti-tus kab mob, ua kom tus kab mob tsis kam

Kev tshawb fawb qhia tau hais tias cov poov xab β-glucan yuav ho ua rau kom cov miv nyuas siv zug ntawm tshuaj tua kab mob; thaum siv nyob rau hauv ua ke nrog nrog tshuaj tua kab mob, nws stimulation ntawm lub luag hauj lwm ntawm macrophages yuav ua rau kom lub kho nyhuv ntawm cov tshuaj. Nyob rau hauv lub β-1,3-D-glucan lug txhim khu lub cev nws tus kheej thiab anti-bacterial muaj peev xwm nyob rau tib lub sij hawm, tshuaj tua kab mob yuav inhibit kab mob aggression, txhim kho lub cev kuj. Nas tsuag peritonitis thwmsim paub tseeb tias cov kev siv ntawm β-1,3-D-glucan ib leeg muaj 80% ciaj sia taus (pab pawg neeg tswj ciaj sia taus tus nqi ntawm 20%), cov kev siv ntawm tshuaj tua kab mob nyob ib leeg pab pawg neeg ciaj sia taus tus nqi ntawm 65%, Thaum lub neej coj siv ob muaj 10match0% ciaj sia taus tus nqi.

1.3 txo cov ntshav lipids

Β-1,3-D-glucan muaj lub luag hauj lwm ntawm haum ntawm cov kua tsib acids thiab cov kua tsib acid feem nyob rau hauv vitro, thiab txhawb cholesterol rau cov kua tsib acid hloov dua siab tshiab, kom muaj lub cev metabolism roj uas txhaws taus. Nicolos thiab lwm yam 15 rog roj txiv neej twb kawm. Nyob rau hauv txoj kev tshawb no, tus neeg mob khaws cia hauv tib lub cev hnyav, uas significantly txo tag nrho cov roj uas txhaws taus cov ntsiab lus los ntawm 8% nyob rau hauv lub xya lub lim tiam thiab 6% nyob rau hauv xya lub lim tiam.